منابع مشابه
Once-daily aminoglycoside administration.
Once-daily aminoglycoside dosing is effective in treating gram-negative infections, including those associated with bones and joints.
متن کاملClinical issues surrounding once-daily aminoglycoside dosing in children.
Aminoglycoside antibiotics are first-line treatment for many infectious diseases in the pediatric population and are effective in adults. The traditional dosing interval in children is every 8-12 hours. Studies in adults reported equivalent efficacy and equal or less toxicity with once-daily regimens. Despite many studies in the adult population, this approach has yet to become standard practic...
متن کاملOnce-daily antiretroviral therapy: Spanish Consensus Statement.
BACKGROUND Administration of antiretroviral therapy (ART) once daily is creating extraordinary interest among the members of the scientific community and also among those who receive the therapy. However, in clinical practice, some doubts remain about its use. OBJECTIVES This document examines the characteristics and possibilities of treatment administered once daily. METHODS Consensus of 2...
متن کاملPharmacokinetics of gentamicin at traditional versus high doses: implications for once-daily aminoglycoside dosing.
Two doses of gentamicin (2 and 7 mg/kg of body weight) were administered to 11 healthy volunteers in a randomized, crossover single-dose study to compare their pharmacokinetics. Doses were infused over 1 h with a syringe infusion pump, and 14 concentrations in sera were obtained over an 8-h period. Concentration in serum versus time data were fitted to a two-compartment pharmacokinetic model. I...
متن کاملOnce-daily versus Divided Dosage Lithium Therapy in Acute Mania
The aim of the study was to compare once-daily with divided dosage lithium treatment in acute mania. In 79 retrospectively studied subjects who met the DSMIII-R criteria for mania, 26 independent and dependent variables were analyzed. The two groups of patients (categorized according to dosage schedule) were broadly comparable with respect to demographic and clinical characteristics. The two gr...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1991
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.35.3.399